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## The Beginning
**The Essence of the Sūktas**: The state of being bound by karma, a state that is unnatural and distorted, and its signs.
**(633)** Just as the imbalance of the bodily elements manifests as disease, so too does the imbalance of the soul's inherent elements manifest as the disease of karma. Just as disease has specific causes, so too does the disease of karma. Just as the accumulation of impurities, the aggravation of karmic poisons, the imbalance of bodily elements, conduct contrary to nature, fear, and anxiety, etc., lead to the manifestation of disease, so too does the accumulation of karmic impurities, the aggravation of karmic poisons like attachment, aversion, and delusion, the imbalance of the soul's inherent elements, conduct contrary to the soul's inherent nature - adharma, the fear of the consequences of one's actions, and the anxiety of not being on the right path, etc., lead to the manifestation of the great disease of karma.
**(1)** Just as disease leads to a weakening of the digestive fire, causing a loss of appetite and a dislike for food, so too does the disease of karma lead to a weakening of the soul's inherent energy, causing a loss of appetite for the path of liberation and a dislike for the supreme reality. Just as disease leads to vomiting, a sign of the body's rejection of the disease, so too does the disease of karma lead to a rejection of the path of liberation and a forgetting of one's true nature. Just as disease leads to constipation or indigestion, so too does the disease of karma lead to the accumulation of karmic impurities or the indigestion of worldly desires.
**(2)** Just as disease causes pain in the heart and shortness of breath, so too does the disease of karma cause pain to the soul and shortness of breath in the pursuit of the right path.
**(3)** Just as disease leads to an increase in vital energy, causing rapid breathing, coughing, and phlegm, so too does the disease of karma lead to an obstruction of the soul's inherent knowledge and vision, causing rapid breathing of birth and death, coughing of karmic poisons, and phlegm of worldly desires.
**(4)** Just as disease leads to the decay and depletion of the body, so too does the disease of karma lead to the decay and depletion of the soul's knowledge body.
**(5)** Just as disease disrupts the flow of pure blood in the body, causing the body to become pale, weak, and lifeless, so too does the disease of karma disrupt the flow of pure consciousness, causing the soul's knowledge body to become pale, weak, and lifeless.
**(6)** Just as disease dries up the bodily elements like blood and flesh, leaving only bones, so too does the disease of karma dry up the soul's inherent elements like knowledge and vision, leaving only a faint trace of consciousness.
**(7)** Just as disease can affect the brain, causing confusion, loss of memory, and incoherent speech, so too does the disease of karma affect the soul, causing confusion, loss of memory, and incoherent speech.