Book Title: Tulsi Prajna 2003 10
Author(s): Shanta Jain, Jagatram Bhattacharya
Publisher: Jain Vishva Bharati

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Page 94
________________ A Review Article Dietary Management of Peptic Ulcer Dr J.P.N. Mishra Peptic ulcer is a break or crate-like lesion in the gastric or duodenal mucosa that arises when the normal defensive factors are impaired or are overwhelmed by aggressive luminal factors such as acid or pepsin. By definition, ulcers extend through the muscularis mucosae and are usually over 5 mm in diameter. Ulcers occure five times more commonly in the duodenum, where 95% are in the bulb or pyloric channel. In the stomatch, benign ulcers are located most commonly in the antrum (60%) and at the junction of the antrum and body on the lesser curvature (25%). Ulcer occur slightly more commonly in men than in women in the ratio of 1.3:1. Alghough ulcer can occure in any age group, duodenal ulcers most commonly occure between the age of 30 and 55, where as gastric ulcers are more common between the ages of 55 and 70. Ulcers are more common in smokers and in patients receiving Non-steroidal Anti-inflamatory Drugs (NSAIDS) on a chronic basis. Alcohol and dietary factors also appear to cause ulcer disease. The role of stress is somehow mysterious. The incidence of duodenal ulcer disease has been declining dramatically for last 30 years, but the incidence of gastric ulcer appears to be increasing, perhaps as a result of the widespread use of NSAIDS. Etiology The disease was once thought to be due to over secretion of acid by the stomatch, but the cause is now known to be more complex. Everyone secretes acid which is an essential component of gastric juice and required for proper digestion. But only 10% people develop THAT Y511 3Taga-faktore, 2003 C - 93 Jain Education International For Private & Personal Use Only www.jainelibrary.org

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